Define
Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is an aggressive and fast-growing type of brain cancer. It is one of the most common and malignant primary tumors of the central nervous system (CNS). GBM originates from glial cells, which are supportive cells in the brain, and particularly from astrocytes (a type of glial cell). GBM is typically found in the frontal and temporal lobes, but can spread to other parts of the brain.
Key characteristics of glioblastoma multiforme include:
-
Rapid growth: GBM grows quickly, often spreading into nearby brain tissue.
-
Invasive nature: It tends to infiltrate the surrounding brain, making complete surgical removal difficult. Local recurrence is very common.
35 in 1,000,000 people will be diagnosed with glioblastoma multiforme.
WHO Grade IV
All GBM tumors are Grade IV malignant, which are the most aggressive and serious type of tumor and cancer due to their rapid growth and infiltrating surrounding tissue, making it difficult to treat.
Statistics to know:
Signs and Symptoms
Neurological Symptoms
-
Headaches
-
Seizures
-
Memory loss or confusion
-
Personality or behavior changes
-
Cognitive decline
Speech and Language Symptoms
-
Difficulty speaking or understanding language
-
Slurred speech
Motor and Sensory Changes
-
Weakness or numbness
-
Loss of coordination or balance
-
Vision and Hearing Problems
-
Loss of peripheral vision
-
Hearing loss (less common)
General Symptoms
-
Nausea and vomiting
-
Fatigue or drowsiness
-
Sleep disturbances